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Soleno Therapeutics Rises as Wolfe Research Gives Positive Outlook

Ellis HobbsAvatar
Written by Ellis Hobbs
Updated 12/13/2025, 8:16 am ET | 5 min

In this article Last trade Dec, 12 6:29 PM

  • SLNO+5.07%
    SLNO - NASDAQSoleno Therapeutics Inc.
    $52.00+2.51 (+5.07%)
    Volume:  1.54M
    Float:  45.44M
    $49.10Day Low/High$52.79

Soleno Therapeutics Inc.’s stocks have been trading up by 5.07 percent fueled by positive market sentiment and promising clinical developments.

Healthcare industry expert:

Analyst sentiment – positive

Market Position & Fundamentals: Soleno Therapeutics (SLNO) demonstrates striking financial metrics. With a gross margin of 98.1%, it suggests efficiency in production and cost control. However, profitability ratios like EBIT and EBITDA margins standing at -76.8 and -74.8, respectively, reflect operational challenges and substantial overhead costs not offset by revenue. The company displays robust asset management with a high current ratio of 16.1 and quick ratio of 15.8, showcasing strong liquidity. Financial strength is further supported by a low total debt to equity ratio of 0.11. Despite these assets, the company’s steep pretax profit margin at -287.7 and negative return on assets at -28.49 highlight a critical need for strategic revenue enhancement. Net income from continuing operations of $26 million reflects inclusive operational adjustments.

Technical Analysis & Trading Strategy: Soleno’s recent stock price behavior highlights critical movements. The week showed a low of $49.21 and a peak at $52, indicating moderate volatility. Volume and price action exhibit consolidation with downward pressure, as seen with a consistent lowering of opening and closing prices across the trading week, until an uptick on the last trading day. A potential head and shoulders pattern demands caution. Technically, a close above $52 could trigger a bullish outlook, whereas a fall below $49 could signal expansive bearish movements. Short-term strategy involves setting a buy-stop order above $52 with a target at $55, while a sell-stop just below $49 could be a judicious short strategy.

Catalysts & Outlook: Recent coverage by Wolfe Research reaffirms market confidence with an ‘Outperform’ rating and a substantial price target enhancement to $75, citing overblown safety concerns. The focus on Soleno’s upward utilization trends suggests a recovering trajectory in new patient starts. Compared to industry and sector benchmarks, Soleno shows a range-bound performance, buffered by impending catalysts. Upside momentum recognized periodically enhances an optimistic outlook for the subsequent years. Strong support is pegged near $50, bolstered by institutional interest potentially igniting price actions toward the $70 mark in line with Wolfe’s forecast. The prevailing sentiment remains cautiously upbeat given expected catalysts.

Candlestick Chart

Weekly Update Dec 08 – Dec 12, 2025: On Saturday, December 13, 2025 Soleno Therapeutics Inc. stock [NASDAQ: SLNO] is trending up by 5.07%! Discover the key drivers behind this movement as well as our expert analysis in the detailed breakdown below.

Quick Financial Overview

Soleno Therapeutics continues its financial journey with metrics that highlight both strength and opportunities for improvement. Its recent trading history displays a fluctuating yet promising dynamic, with the stock closing at $52 on December 12, after an upward trajectory from $49.21 just days prior. Despite these fluctuations, the company displays solid liquidity with a current ratio of 16.1, emphasizing its ability to meet short-term obligations efficiently.

Analyzing key ratios, Soleno showcases a gross margin of 98.1%, an impressive figure shadowed by negative profit margins such as the pretax profit margin sitting at -287.7%. This suggests a strategic pivot may be necessary to convert the high product profitability into overall company profitability. From a balance sheet perspective, its total assets stand robust at $599.9M, with an overwhelming cash and cash equivalents position of $246.7M, giving it a strong footing to reinvest in growth initiatives.

More Breaking News

The latest financial report reveals positive cash flow improvements with cash position shifts from negative to an ending position of $158.7M. Soleno’s mixed financial landscape, with its sizeable enterprise value of $1.48B and ongoing stock-based compensation expenses contributing to notable costs, remains an area for strategic evaluation.

Conclusion

The market paints a promising picture for Soleno Therapeutics, characterized by an optimistic evaluation from Wolfe Research and clear insights into future advancements. The current bullish sentiment captured by the analysts indicates strategic revitalization measures are underway to address recent geometric challenges. As the company latches onto improving trends, patient growth levels are expected to follow suit, potentially driving stock stabilization and value enhancement going forward. As millionaire penny stock trader and teacher Tim Sykes says, “Preparation plus patience leads to big profits.” Traders and stakeholders should monitor how these strategic focus points evolve in context with the company’s financial health and broader market fluctuations, applying patience and preparation as they navigate these promising developments.

This is stock news, not investment advice. Timothy Sykes News delivers real-time stock market news focused on key catalysts driving short-term price movements. Our content is tailored for active traders and investors seeking to capitalize on rapid price fluctuations, particularly in volatile sectors like penny stocks. Readers come to us for detailed coverage on earnings reports, mergers, FDA approvals, new contracts, and unusual trading volumes that can trigger significant short-term price action. Some users utilize our news to explain sudden stock movements, while others rely on it for diligent research into potential investment opportunities.

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Ellis Hobbs

Trainer and Mentor on Tim Sykes’ Trading Challenge
He teaches webinars on Tim Sykes’ Trading Challenge He treats trading like a business, not a hobby He emphasizes taking small risks — “If you get the process right, money is a forgone conclusion.”
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* Results are not typical and will vary from person to person. Making money trading stocks takes time, dedication, and hard work. There are inherent risks involved with investing in the stock market, including the loss of your investment. Past performance in the market is not indicative of future results. Any investment is at your own risk. See Terms of Service here

The available research on day trading suggests that most active traders lose money. Fees and overtrading are major contributors to these losses.

A 2000 study called “Trading is Hazardous to Your Wealth: The Common Stock Investment Performance of Individual Investors” evaluated 66,465 U.S. households that held stocks from 1991 to 1996. The households that traded most averaged an 11.4% annual return during a period where the overall market gained 17.9%. These lower returns were attributed to overconfidence.

A 2014 paper (revised 2019) titled “Learning Fast or Slow?” analyzed the complete transaction history of the Taiwan Stock Exchange between 1992 and 2006. It looked at the ongoing performance of day traders in this sample, and found that 97% of day traders can expect to lose money from trading, and more than 90% of all day trading volume can be traced to investors who predictably lose money. Additionally, it tied the behavior of gamblers and drivers who get more speeding tickets to overtrading, and cited studies showing that legalized gambling has an inverse effect on trading volume.

A 2019 research study (revised 2020) called “Day Trading for a Living?” observed 19,646 Brazilian futures contract traders who started day trading from 2013 to 2015, and recorded two years of their trading activity. The study authors found that 97% of traders with more than 300 days actively trading lost money, and only 1.1% earned more than the Brazilian minimum wage ($16 USD per day). They hypothesized that the greater returns shown in previous studies did not differentiate between frequent day traders and those who traded rarely, and that more frequent trading activity decreases the chance of profitability.

These studies show the wide variance of the available data on day trading profitability. One thing that seems clear from the research is that most day traders lose money .

Millionaire Media 66 W Flagler St. Ste. 900 Miami, FL 33130 United States (888) 878-3621 This is for information purposes only as Millionaire Media LLC nor Timothy Sykes is registered as a securities broker-dealer or an investment adviser. No information herein is intended as securities brokerage, investment, tax, accounting or legal advice, as an offer or solicitation of an offer to sell or buy, or as an endorsement, recommendation or sponsorship of any company, security or fund. Millionaire Media LLC and Timothy Sykes cannot and does not assess, verify or guarantee the adequacy, accuracy or completeness of any information, the suitability or profitability of any particular investment, or the potential value of any investment or informational source. The reader bears responsibility for his/her own investment research and decisions, should seek the advice of a qualified securities professional before making any investment, and investigate and fully understand any and all risks before investing. Millionaire Media LLC and Timothy Sykes in no way warrants the solvency, financial condition, or investment advisability of any of the securities mentioned in communications or websites. In addition, Millionaire Media LLC and Timothy Sykes accepts no liability whatsoever for any direct or consequential loss arising from any use of this information. This information is not intended to be used as the sole basis of any investment decision, nor should it be construed as advice designed to meet the investment needs of any particular investor. Past performance is not necessarily indicative of future returns.

Citations for Disclaimer

Barber, Brad M. and Odean, Terrance, Trading is Hazardous to Your Wealth: The Common Stock Investment Performance of Individual Investors. Available at SSRN: “Day Trading for a Living?”

Barber, Brad M. and Lee, Yi-Tsung and Liu, Yu-Jane and Odean, Terrance and Zhang, Ke, Learning Fast or Slow? (May 28, 2019). Forthcoming: Review of Asset Pricing Studies, Available at SSRN: “https://ssrn.com/abstract=2535636”

Chague, Fernando and De-Losso, Rodrigo and Giovannetti, Bruno, Day Trading for a Living? (June 11, 2020). Available at SSRN: “https://ssrn.com/abstract=3423101”

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