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Can PHIO Bounce Back?

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Written by Timothy Sykes Reviewed by Jack Kellogg Fact-checked by Ellis Hobbs
Updated 11/3/2025, 5:04 pm ET 11/3/2025, 5:04 pm ET | 5 min 5 min read
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Phio Pharmaceuticals Corp’s stocks have been trading down by -10.49 percent amid potential shifts in strategic direction.

  • The company’s trading volume spiked, indicating significant interest. Over 5M shares exchanged at peak hours, indicating increased trader interest or panic selling.

  • Discussions among traders highlight the lack of recent positive catalysts. PHIO has faced challenges, reflecting in its volatile stock price.

  • Investors watched closely as the company’s largest trades took place between $2.00 to $3.00 but closed under their opening, suggesting market uncertainty.

Candlestick Chart

Live Update At 17:04:22 EST: On Monday, November 03, 2025 Phio Pharmaceuticals Corp. stock [NASDAQ: PHIO] is trending down by -10.49%! Discover the key drivers behind this movement as well as our expert analysis in the detailed breakdown below.

Recent Financial Performance

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Phio Pharmaceuticals Corp., a niche player in the biotech space, recently released its quarterly financials on Jun 30, 2025. The figures are painting a less-than-rosy picture. Their operating loss stood at nearly $2.31M with revenue streams still under development. The loss raises eyebrows considering high operational expenditures—just north of $2M.

A healthy current ratio of 9.4 means the firm’s short-term liabilities are well-covered, but the negative return on assets at -63.76% signals inefficiency. Delving into cash flow, the company has a cash burn of approximately $2.54M this quarter. With cash reserves of about $10.77M, they hold a decent runway. But caution is necessary as the operational hemorrhage continues.

PHIO shows no signs yet of diving into the dividend pool, making it less appealing for long-term, yield-seeking investors. The backdrop of heavy R&D investments creates a classic high-risk, high-reward scenario typical of the biotech sector.

Meaning Behind the Numbers

The steep decline can be traced to PHIO’s inability to generate consistent revenue, coupled with significant operational losses. With almost all financial ratios in the red, potential investors remain skeptical. But why this erratic fluctuation?

Reports suggest a possible linkage to the recent market trends in the biotech sector, where penny stocks are being impacted by regulatory shifts. Changes in drug approvals, trials, and market sentiment toward biotechnological advancements play significant roles. Additionally, PHIO’s focus on innovative treatments demands heavy investment, often without immediate returns, spotlighting the balance between innovation and financial prudence.

Despite fluctuating prices, some analysts remain hopeful as they zoom in on the proprietary nature of the innovations at Phio. While these prospects might urge risk-takers to acquire stock amidst prevailing price lows, cautious investors are urged to observe from the sidelines.

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Conclusion

Phio Pharmaceuticals is undoubtedly navigating turbulent waters; however, the journey of a biotech enterprise capturing the spark of innovation is rarely smooth. Market forces, internal trials, and external factors make it a challenging landscape. With management pulling all stops to stabilize finances, the challenge remains to translate novel scientific advancements into revenue-generating products. As millionaire penny stock trader and teacher Tim Sykes says, “Small gains add up over time; focus on building wealth gradually, not chasing jackpots.” This wisdom could be pivotal for PHIO, as traders watch closely to see if slow, strategic efforts underpinned by this mindset can yield resurgence or if the coming quarters will reveal another setback in this fast-evolving market.

This is stock news, not investment advice. Timothy Sykes News delivers real-time stock market news focused on key catalysts driving short-term price movements. Our content is tailored for active traders and investors seeking to capitalize on rapid price fluctuations, particularly in volatile sectors like penny stocks. Readers come to us for detailed coverage on earnings reports, mergers, FDA approvals, new contracts, and unusual trading volumes that can trigger significant short-term price action. Some users utilize our news to explain sudden stock movements, while others rely on it for diligent research into potential investment opportunities.

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Tim Sykes

Head Writer at TimothySykes.com, Lead Mentor at the Trading Challenge
In his 20-plus years of trading, Tim has made $7.9 million. In his 15-plus years of teaching, Tim’s Trading Challenge has produced over 30 millionaire students. His philosophy emphasizes small gains and cutting losses quickly.
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* Results are not typical and will vary from person to person. Making money trading stocks takes time, dedication, and hard work. There are inherent risks involved with investing in the stock market, including the loss of your investment. Past performance in the market is not indicative of future results. Any investment is at your own risk. See Terms of Service here

The available research on day trading suggests that most active traders lose money. Fees and overtrading are major contributors to these losses.

A 2000 study called “Trading is Hazardous to Your Wealth: The Common Stock Investment Performance of Individual Investors” evaluated 66,465 U.S. households that held stocks from 1991 to 1996. The households that traded most averaged an 11.4% annual return during a period where the overall market gained 17.9%. These lower returns were attributed to overconfidence.

A 2014 paper (revised 2019) titled “Learning Fast or Slow?” analyzed the complete transaction history of the Taiwan Stock Exchange between 1992 and 2006. It looked at the ongoing performance of day traders in this sample, and found that 97% of day traders can expect to lose money from trading, and more than 90% of all day trading volume can be traced to investors who predictably lose money. Additionally, it tied the behavior of gamblers and drivers who get more speeding tickets to overtrading, and cited studies showing that legalized gambling has an inverse effect on trading volume.

A 2019 research study (revised 2020) called “Day Trading for a Living?” observed 19,646 Brazilian futures contract traders who started day trading from 2013 to 2015, and recorded two years of their trading activity. The study authors found that 97% of traders with more than 300 days actively trading lost money, and only 1.1% earned more than the Brazilian minimum wage ($16 USD per day). They hypothesized that the greater returns shown in previous studies did not differentiate between frequent day traders and those who traded rarely, and that more frequent trading activity decreases the chance of profitability.

These studies show the wide variance of the available data on day trading profitability. One thing that seems clear from the research is that most day traders lose money .

Millionaire Media 66 W Flagler St. Ste. 900 Miami, FL 33130 United States (888) 878-3621 This is for information purposes only as Millionaire Media LLC nor Timothy Sykes is registered as a securities broker-dealer or an investment adviser. No information herein is intended as securities brokerage, investment, tax, accounting or legal advice, as an offer or solicitation of an offer to sell or buy, or as an endorsement, recommendation or sponsorship of any company, security or fund. Millionaire Media LLC and Timothy Sykes cannot and does not assess, verify or guarantee the adequacy, accuracy or completeness of any information, the suitability or profitability of any particular investment, or the potential value of any investment or informational source. The reader bears responsibility for his/her own investment research and decisions, should seek the advice of a qualified securities professional before making any investment, and investigate and fully understand any and all risks before investing. Millionaire Media LLC and Timothy Sykes in no way warrants the solvency, financial condition, or investment advisability of any of the securities mentioned in communications or websites. In addition, Millionaire Media LLC and Timothy Sykes accepts no liability whatsoever for any direct or consequential loss arising from any use of this information. This information is not intended to be used as the sole basis of any investment decision, nor should it be construed as advice designed to meet the investment needs of any particular investor. Past performance is not necessarily indicative of future returns.

Citations for Disclaimer

Barber, Brad M. and Odean, Terrance, Trading is Hazardous to Your Wealth: The Common Stock Investment Performance of Individual Investors. Available at SSRN: “Day Trading for a Living?”

Barber, Brad M. and Lee, Yi-Tsung and Liu, Yu-Jane and Odean, Terrance and Zhang, Ke, Learning Fast or Slow? (May 28, 2019). Forthcoming: Review of Asset Pricing Studies, Available at SSRN: “https://ssrn.com/abstract=2535636”

Chague, Fernando and De-Losso, Rodrigo and Giovannetti, Bruno, Day Trading for a Living? (June 11, 2020). Available at SSRN: “https://ssrn.com/abstract=3423101”